Fucoidan Ameliorates Ferroptosis in Ischemia-reperfusion-induced Liver Injury through Nrf2/HO-1/GPX4 Activation
نویسندگان
چکیده
Background and AimsLiver ischemia-reperfusion (IR) injury is a common pathological process in liver surgery. Ferroptosis, which closely related to lipid peroxidation, has recently been confirmed be involved the pathogenesis of IR injury. However, development drugs that regulate ferroptosis slow, complete understanding mechanisms underlying not yet achieved. Fucoidan (Fu) sulfated polysaccharide attracted research interest due its advantages easy access wide biological activity.
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ژورنال
عنوان ژورنال: Journal of clinical and translational hepatology
سال: 2023
ISSN: ['2310-8819', '2225-0719']
DOI: https://doi.org/10.14218/jcth.2023.00133